Periodontitis Research Today is a free monthly online journal that collates and summarizes the latest research about Periodontitis, including details on treatment, causes, gingivitis, symptoms. | ||||||||
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Periodontal pathogens in atheromatous plaques isolated from patients with chronic periodontitis.Padilla C, Lobos O, Hubert E, González C, Matus S, Pereira M, Hasbun S, Descouvieres C Laboratorio de Investigación Microbiológica, Universidad de Talca, Talca, Chile. cpadilla@utalca.cl BACKGROUND AND OBJECTIVE: It has been suggested that chronic infections may predispose to cardiovascular disease. The relationship between periodontal disease and cardiovascular disease has been a subject of increasing research in recent years. The isolation and identification of periodontal bacteria from atheromatous plaque can contribute to our knowledge of this vascular disease. The aim of this study was to isolate and identify periodontal bacteria from the periodontal pockets of different patients and to compare them with the microorganisms detected in the atheromatous plaques obtained from the same patients. MATERIAL AND METHODS: Clinical isolates were obtained from 12 patients with periodontal wounds and atheromathous plaques. These samples were cultured in the appropriate bacteriological culture media and incubated in an anaerobic system. Periodontal bacteria were identified using polymerase chain reaction (PCR) assays. RESULTS: From the 12 patients studied, nine presented different periodontopathic bacterial species. In two, Actinobacillus actinomycetemcomitans was present in the periodontal pockets and the respective atheromatous plaques. CONCLUSION: The presence of A. actinomycetemcomitans in atheromatous plaques and the periodontal pockets of the same patients could indicate a role for periodontal pathogenic bacteria in the atherosclerosis disease process. Published 10 July 2006 in J Periodontal Res, 41(4): 350-3.
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